Biomarkers for Colorectal Cancer in Blood Samples

miRNAs in blood-borne exosomes can be used to detect the presence and stage of colorectal cancer

by Science Writer Kim Woolcock

Depiction of exosome

Colorectal cancer (CRC) is the third most common cancer, and early diagnosis and staging can greatly improve the prognosis. Tahani Bakhsh, PhD, at the University of Jeddah and Ahmed Bahieldin, PhD, at King Abdulaziz University in Saudi Arabia and coworkers have identified new biomarkers for CRC that may help improve diagnosis and staging. The biomarkers are microRNAs (miRNAs), short non-coding RNAs, which are present in blood samples, making them minimally invasive to collect. The results were published in a paper entitled “Molecular Detection of Exosomal miRNAs of Blood Serum for Prognosis of Colorectal Cancer”in Scientific Reports on April 17, 2024.

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