Cancer research continues to accelerate as researchers around the world report ground-breaking advances in new treatments for all types of cancer. The progress is strongly reflected in the quality and quantity of clinical trials submitted for presentation at the American Association for Cancer Research (AACR) Annual Meeting 2023 (April 14-19), according to Timothy A. Yap, MD, PhD, Associate Professor, Department of Investigational Cancer Therapeutics, and Medical Director, Institute for Applied Cancer Science, at the University of Texas MD Anderson Cancer Center. Dr. Yap serves as co-chair of the AACR Annual Meeting Clinical Trials Committee alongside Shivaani Kummar, MD, DeArmond Endowed Chair of Cancer Research, Co-Director of the Center for Experimental Therapeutics, and Deputy Director for Clinical & Translational Research, Knight Cancer Institute at Oregon Health & Science University (OHSU). Along with the clinical trials presented during the daily plenaries, symposia, and poster sessions, the Annual Meeting program features three clinical trials minisymposia and four in-depth clinical trials plenary sessions that will include paired presentations on the science behind the trials. For more information, see below.