A Method to Access Genetic Information in Blood Samples and Find Correlations with Mental Health Problems; Researchers in Brazil Evaluated MicroRNA (miRNA) Contained in Extracellular Vesicles (EVs) Possibly Secreted By Brain Tissue

Using blood samples to study diseases that originate in the brain is a difficulty faced by psychiatric genetics in the search for markers of mental health disorders. Researchers at the Federal University of São Paulo (UNIFESP) in Brazil have shown that this hindrance can be surmounted by analyzing microRNAs in extracellular vesicles (EVs), which are produced by most cells in the body, including neurons and other nervous system cells. The study was supported by FAPESP and is reported in an article published on February 6, 2023 in Translational Psychiatry. The open-acccess article is titled “Alterations in MicroRNA of Extracellular Vesicles Associated with Major Depression, Attention-Deficit/Hyperactivity and Anxiety Disorders in Adolescents.”
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