On October 4, 2021, the Nobel Assembly at Karolinska Institutet announced its decision to award the 2021 Nobel Prize in Physiology or Medicine jointly to David Julius, PhD, and Ardem Patapoutian, PhD, for their discoveries of receptors for temperature and touch. Our ability to sense heat, cold and touch is essential for survival and underpins our interaction with the world around us. In our daily lives, we take these sensations for granted, but how are nerve impulses initiated so that temperature and pressure can be perceived? This mystery has been solved by this year’s Nobel laureates.
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